Chromium Single Cell

Every cell has a story. Tell them all with  Chromium.

Single cell analysis enables meaningful discoveries

Bulk sequencing averages readouts, missing critical details driving complex biology. Single cell sequencing allows scientists to see the unique gene expression patterns of each cell. This view more fully characterizes tissue heterogeneity, revealing the rare cell types that have big consequences in health and disease

Platform Components

A complete solution from tissue to insight.

The product page should make the individual components easy to understand and navigate.

 

Gene & Protein Panels

Customizable ready-to-use panels or fully custom gene panels with add-on protein subpanels

Xenium Analyzer instrument

Industry-leading speed and throughput for single cell spatial imaging

Data Analysis

Powerful on-board analysis and Xenium Explorer visualization software

Innovations

Innovations developed for your success at every step

Our world-class support team is here to boost your success from sample prep to data analysis.
 
 
 

Access more sample types

Profile fresh, frozen, or fixed samples—even FFPE—with optimized protocols for proven performance

Automate critical steps to reduce error

Produce up to 8M barcoded partitions in just minutes, with up to 80% cell recovery

Construct high-quality sequence-ready libraries

Generate libraries with up to 95% usable reads, letting you detect more genes at lower sequencing costs

Analyze & discover with ease

Process and visualize your data with powerful software tools—no bioinformatics experience required

Broad, flexible portfolio of assays

Our world-class support team is here to boost your success from sample prep to data analysis.
 
 
 

Flex

Fix, batch, and run on your schedule.

  • Protein coding gene coverage: Performs well with low-quality and FFPE samples
  • Multiomic readouts from the same cell: Gene expression, Protein, CRISPR
  • Throughput options: Up to 8M cells (1–3,072 samples) per run

Universal

Species agnostic. Maximum versatility.

  • Whole transcriptome coverage: Delivers broadest set of information, including isoforms, SNPs, etc.
  • Multiomic readouts from the same cell: 3' or 5' gene expression, TCR/BCR, Protein, CRISPR
  • Throughput options: Up to 160,000 cells (1–8 samples) per run

Epi Chromatin

Unmask epigenomic profiles.

  • ATAC-seq chemistry: Explore open chromatin regions and link directly to 3' gene expression (Multiome kit)
  • Multiomic readouts from the same cell: Chromatin accessibility, 3' gene expression
  • Throughput options: Up to 80,000 nuclei (1–8 samples) per runUp to 8M cells (1–3,072 samples) per run

During the past years, we observed many advances in single cell technologies thanks to 10x Genomics. This multi-omics approach is very useful for scientists and for physicians to understand human disorders.

David Michonneau, PhD
Professor of Hematology at Saint-Louis Hospital

Applications

Amplify your research gains

Access the greatest application breadth on the market with superior multiomic integration and 40+ demonstrated protocols.
 
 

Gene expression

Characterize the unique transcriptomic profiles of each cell in your sample

Immune profiling

Obtain functional data for antibody/TCR discovery

CRISPR screening

Directly link CRISPR guide RNAs to the resulting perturbed phenotypes

advantage

Bring the Chromium advantage to your lab

Explore the resources below to learn more about your options and how to get started.
 

Practical considerations and best practices for getting started

Introduction to GEM-X

Grant writing assistance

Buyer's Guide

Vision Diagnostic

Bring Xenium to your laboratory.

Talk to our scientific and technical team about product selection, panels, applications, pricing and implementation support.