Visium Spatial Platform

Whole transcriptome spatial discovery

Best-in-class spatial data quality with complete coverage

The Visium platform delivers unbiased, whole transcriptome spatial gene expression analysis at single cell scale with unmatched spatial data quality and offers a flexible assay portfolio to study a broad range of tissues and species.
 

Advantage

A complete solution from tissue to insight.

Visium slides and reagents

High-resolution, whole transcriptome spatial gene expression across species and tissue conditions

Visium CytAssist instrument

Enables a histology-friendly workflow and provides high spatial fidelity

Data analysis

Free, easy-to-use software for intuitive data visualization and exploration

New! Visium HD 11 mm slides

Bring more HD biology into focus

A

Maximize biological context for large tissues, including human brain or tumors with surrounding stroma

B

Unlock sample multiplexing for smaller tissue sections, including TMAs

C

Achieve the highest Visium HD WT Panel sensitivity with the new protocol 2.0

Whole transcriptome spatial biology at the resolution you need

Our Visium HD product line offers a distinct slide architecture and two chemistries to explore the whole transcriptome spatial biology of your samples at the resolution you need.
 
 
 
 
 

Visium HD WT Panel

Recommended for differential gene expression in human, mouse, and rat

  • Protein coding gene coverage: Optimized for archival and FFPE samples
  • Flexible tissue compatibility: Compatible with FFPE, fresh frozen, and fixed frozen tissues

Visium HD 3'

Recommended for expanded discovery applications

  • Whole transcriptome coverage: Delivers de novo discovery power
  • Explore across species: Tested in human, mouse, rat, pig, non-human primate and more

Unmatched spatial data quality with a histology-friendly workflow

  • Ensure high spatial fidelity through precise transcript localization facilitated by the Visium CytAssist instrument
  • Leverage a standard histological workflow to section, stain, and image tissues directly on glass slides
  • Pre-screen and orient tissue sections to align the most desired region of tissue onto the Capture Area of the Visium slide

Accelerate spatial discovery with intuitive data exploration

Simple, fast analysis with Space Ranger

  • Upload FASTQ files to 10x Cloud Analysis or download our free software for local analysis
  • Process spatial sequencing data with imaging data in minutes with no command line required, including cell segmentation and annotation

Immediate insights with powerful data visualization

  • Visualize and explore thousands of spatially variable genes in a few clicks with Loupe Browser
  • Explore gene expression clusters in the tissue context to define cell types or gene signatures by region and morphology

Resources

See Visium HD data in action

Learn how to map the tumor microenvironment of colorectal cancer with the Visium HD assay and Loupe Browser in this guided data tutorial.

Grant writing assistance

Get the information you need to write grants featuring Visium experiments (including technology overview, benchmarking data, and more).

Spatial publications

Browse peer-reviewed publications to see how researchers have used Visium Spatial technology to accelerate novel discoveries.

Unlock the full spectrum of biology

Elevate your Visium Spatial insights with comprehensive single cell analysis or targeted, precision insights into the tissue context.

Platform

Chromium Single Cell platform

Visium Spatial platform

Xenium Spatial platform
When to use Comprehensive single cell data Ideal for deep characterization of cell populations and states. High-resolution spatial gene expression Understand complex tissues, neighborhoods, and cell to cell interactions. Integration with other spatial-omics, histology, and morphology.
Why to use Unbiased single cell discovery High per-gene sensitivity Unbiased spatial discovery Targeted spatial exploration High per-gene sensitivity
Applications Whole transcriptome gene expression Protein TCR, BCR CRISPR ATAC Whole transcriptome gene expression Targeted gene expression (up to 5,000 genes)
Resolution Single cell Transcripts assigned to 2-µm areas Single cell
Data readout NGS-based NGS-based Imaging-based
Sample compatibility Single cell or nuclei suspensions from fresh, frozen, or FFPE samples FFPE Fresh frozen Fixed frozen Fresh frozen FFPE

Vision Diagnostic

Bring Visium to your laboratory.

Talk to our scientific and technical team about product selection, panels, applications, pricing and implementation support.