Competent Cells for High Throughput Cloning
Scalable cell therapy solutions for your manufacturing workflow
Scalable, modular systems support consistent cell therapy manufacturing from research through clinical production. These connected solutions help improve reproducibility and support building regulatory confidence across many stages of your bioprocessing workflow. Our solutions span beyond cell isolation, activation, and expansion, enabling process consistency and cGMP-ready performance. Built with cGMP manufacturing and automation compatibility, Gibco cell therapy products help simplify workflow transitions and scale with your program. Backed by decades of experience in cell therapy, we support your progress toward reliable, patient-ready therapies.
CTS DynaCellect Magnetic Separation System
Built to automate closed, high-throughput isolation of T cells to help improve consistency and reduce manual handling. The Gibco CTS DynaCellect Magnetic Separation System facilitates scale-up for clinical manufacturing and supports standardized, cGMP-ready workflows.
Dynabeads magnetic beads
Available in two formats, Dynabeads magnetic beads support precise isolation and activation of T cells for reliable therapy development. Gibco CTS Dynabeads magnetic beads facilitate controlled stimulation and expansion, while Gibco CTS Detachable Dynabeads magnetic beads help add process flexibility with an active release mechanism for workflows.
Cell therapy bag assemblies
Learn more about one-step PCR cloning that combines traditional restriction and ligation cloning.
Cell therapy media
Support high cell viability and growth throughout development and manufacturing. cGMP-produced Gibco OpTmizer cell therapy media promote consistent performance and scalability, enabling a smooth transition from process development to clinical and commercial production.
Cell therapy reagents
Developed to preserve cell quality and purity across connected workflows. Gibco CTS reagents are manufactured under cGMP conditions with complete traceability to help support reliable, compliant cell processing from development through manufacturing.
CTS DynaMag magnet
Enable closed, scalable magnetic isolation and activation of T cells. Designed for use with Dynabeads magnetic beads, Gibco DynaMag magnets strengthen reproducible, cGMP-ready processing for clinical research and resource-limited manufacturing environments.
Discover cell therapy bioprocessing solutions
Explore cell therapy bioprocessing solutions that help maintain consistency as programs progress from development to manufacturing and adapt to autologous or allogeneic needs.
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CTS Rotea Counterflow Centrifugation System
Designed to automate cell washing, concentration, and separation with gentle counterflow technology that helps maintain cell viability. The Gibco CTS Rotea System supports closed, single-use processing for CAR-T, stem-cell, and PBMC applications, helping standardize scale-up and CGMP documentation.
CTS Xenon Electroporation System
Facilitate delivery of DNA, RNA, and proteins efficiently into hard-to-transfect cells while maintaining viability with the Gibco CTS Xenon Electroporation System. Two single-use chamber formats help streamline development and commercial-scale runs.
Closed System Media and Reagents
Support CGMP-ready manufacturing in sterile, closed workflows with Gibco media and reagents. These formulations maintain cell function through isolation, expansion, and cryopreservation, allowing documentation that simplifies verification and technology transfer.
What are the challenges to scaling a cell therapy process?
Scaling a cell therapy manufacturing process introduces technical, operational, and regulatory challenges. The variability of patient- or donor-derived starting material makes it difficult to maintain product quality and cell phenotype. Manual and open steps add complexity and increase the chance of variation between runs. As production expands, these factors drive manufacturing costs and strain facility capacity.
Meeting regulatory expectations and managing material logistics adds further pressure. Every stage from raw material sourcing to cold-chain distribution requires precise control and documentation. Without early standardization, these hurdles can increase the cost of goods (COGs) and limit how quickly therapies reach patients.
How do closed and automated systems improve cell therapy workflows?
Closed and automated systems strengthen control across many stages of cell processing, from isolation and modification to expansion. By helping to minimize manual transfers, they can lower contamination risk and improve operator safety. Automation supports consistent timing, temperature, and mixing, which help enhance processes and reproducibility across runs.
These systems can also make scale-up more efficient by reducing the number of hands-on steps and offering reliable, traceable data for cGMP documentation. These are designed to lower manufacturing cost, facilitate faster turnaround, and promote higher product quality, which are key factors in making advanced therapies more accessible to patients.
What types of cell therapy products are designed for processing and analytics?
Reliable cell therapy manufacturing depends on systems that maintain process control and verify product quality from start to finish. Tools for closed-system processing and analytical testing work together to enhance quality assurance and support cGMP compliance across the workflow:
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